Flood and Scanning Technology


We have access to both flood and scanning technologies, both for adaptive optics and optical coherence tomography imaging.



Twenty-five years of clinical applications using adaptive optics ophthalmoscopy

Jessica I. W. Morgan, Toco Y.P. Chui, Kate Grieve
Biomedical Optics Express
January 2023

Time-lapse imaging of geographic atrophy

Michel Paques, Nathaniel Norberg, Celine Chaumette, Florian Sennlaub, Ethan A. Rossi, Ysé Borella, Kate Grieve
22nd June 2022

Imaging the structure and dynamic activity of retinal microglia and macrophage-like cells in the living human eye

Yuhua Rui, Daniel MW Lee, Min Zhang, Valerie C Snyder, Rashmi Raghuraman, Elena Gofas, Pedro Mecê, Sanya Yadav, Pavan Tiruveedhula, Kate Grieve, José-Alain Sahel, Marie-Hélène Errera, Ethan A Rossi
15th June 2022

Design of a radial multi-offset detection pattern for in vivo phase contrast imaging of the inner retina in humans

Elena Gofas, Yuhua Rui, Pedro Mecê, Min Zhang, Valerie C. Snyder, Kari V. Vienola, Daniel M. W. Lee, José-Alain Sahel, Kate Grieve, Ethan A Rossi
Biomed. Opt. Express 13, 117-132 , 15th June 2022

Imaging retinal microglial cell dynamics in healthy and diseased eyes in vivo with adaptive optics

Ethan Rossi*, Yuhua Rui, Daniel MW Lee, Min Zhang, Valerie Snyder*, Elena Gofas, Pedro Mecê, Rashmi Raghuraman, Sanya Yadav, Pavan Tiruveedhula, Kate Grieve, Marie-Hélène Errera
1st June 2022

Detecting inflammatory cells in patients with Multiple Sclerosis using AO-SLO phase contrast imaging

Elena Gofas, Celine Louapre, Nathaniel Norberg, Ysoline Beigneux, Michel Paques, Catherine Vignal Clermont, Kate Grieve
Investigative Ophthalmology & Visual Science
1st June 2022

Reactivating the phototransduction cascade by universally applicable gene therapy preserves retinal function in Rod-Cone dystrophy

Cardillia-Joe Simon, Hanen Khabou, Marion Finzi, Antoine Chaffiol, Kate Grieve, Nathaniel Norberg, Anais Grimaud, Dennis Eickelbeck, Marco Rucli, Mélissa Desrosiers, Serge Sancho, Vera Bonilha, Saddek Mohand-Said, Jens Duebel, Serge Picaud, José-Alain Sahel, Isabelle Audo, Stefan Herlitze, Deniz Dalkara
17th January 2022

Partial-Field Illumination Ophthalmoscope: improving the contrast of a camera-based retinal imager

Lea Krafft, Elena Gofas, Yann Lai-Tim, Michel Paques, Laurent Mugnier, Olivier Thouvenin, Pedro Mecê, Serge Meimon
2nd September 2021

Unsupervised Approaches for the Segmentation of Dry ARMD Lesions in Eye Fundus cSLO Images

Clément Royer, Jérémie Sublime, Florence Rossant, Michel Paques
Journal of Imaging
1st August 2021

Adaptive optics scanning laser ophthalmoscopy (AOSLO) measures in USH2A-related retinal degeneration

Jacque Duncan, Zendi Liang, Joseph Carroll, Jenna Cava, Jessica Wong, Michel Michaelides, Angelos Kalitzeos, Isabelle Audo, Kate Grieve, Nathaniel Norberg, Michel Paques, Allison Ayala, Travis Porco
Investigative Ophthalmology & Visual Science
21st June 2021

Enhancing contrast of in-vivo human retinal ganglion cells with multi-offset adaptive optics scanning laser ophthalmoscope

Elena Gofas, Yuhua Rui, Pedro Mecê, Min Zhang, Valerie Snyder, Kari V Vienola, Daniel Lee, José-Alain Sahel, Kate Grieve, Ethan Rossi
12th April 2021

Optical Incoherence Tomography: a method to generate tomographic retinal cross-sections with non-interferometric imaging systems

August 2020

Near infrared adaptive optics flood illumination retinal angiography

Elena Gofas, Pedro Mecê, Laurent Mugnier, Aurélie Montmerle Bonnefois, Cyril Petit, Kate Grieve, José-Alain Sahel, Michel Paques, Serge Meimon
"Near infrared adaptive optics flood illumination retinal angiography," Biomed. Opt. Express 10, 2730-2743 (2019)
1st June 2019

Higher adaptive optics loop rate enhances axial resolution in nonconfocal ophthalmoscopes

"Higher adaptive optics loop rate enhances axial resolution in nonconfocal ophthalmoscopes," Opt. Lett. 44, 2208-2211 (2019)
1st May 2019
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