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IHU i2Eye

 

Thanks to IHU FOReSIGHT funded i2Eye project 2018-2023, we developed breakthrough technologies for exploring the human eye such as laser Doppler holography; clearing of entire human eyes and contributed to the development of adaptive optics–enhanced optical coherence tomography, all being now developed with industry.

Thanks to IHU FOReSIGHT funded i2Eye project 2018-2023, we developed breakthrough technologies for exploring the human eye such as laser Doppler holography; clearing of entire human eyes and contributed to the development of adaptive optics–enhanced optical coherence tomography, all being now developed with industry.
 
Major outputs of i2Eye
-First application of Structured Illumination Microscopy (SIM) to in-vivo imaging of the human retina (Lai Tim et al., 2019)
-Development of full field optical coherence tomography device for clinical use (Scholler et al, Optics Express 2020) and for in vitro non-destructive analysis of cells
-Design of a new method for identification of the earliest drusen (Rossi et al. 2021)
-Detection of novel biomarkers of inflammation during optic neuropathies by adaptive optics scanning laser ophthalmoscopy (Gofas et al IOVS 2022) and setup of a catalog of biomarkers for a variety of human diseases
-Identification of a novel mechanism of RPE atrophy expansion (Paques et al. 2022)
-First demonstration of measurement of blood flow by holographic Doppler imaging in humans (2023)
-First demonstration of the feasibility of clearing of entire human eyes (Darche et al, Communication Biology 2023)
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