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Kate Grieve is the Scientific Director of the Paris Eye Imaging unit.

Since 2014 she has been responsible for development and application of in vivo high resolution ocular imaging technologies at the Quinze Vingts National Ophthalmology Hospital and Vision Institute. She is a leading specialist in both full field optical coherence tomography, in collaboration with Claude Boccara and team at the Langevin Institute, and in adaptive optics technology, as a postdoc with Austin Roorda at UC Berkeley and Martin Booth at University of Oxford, and in current collaboration with Ethan Rossi at University of Pittsburgh Medical Center and Serge Meimon at ONERA. She has successfully completed and is currently principal or co-investigator on various ANR, European Research Council, FFB and internally funded grants to develop optical imaging technologies for ophthalmology and vision applications. In addition to her academic activities, she has worked in industry as an optical engineer, commercializing innovative retinal imaging technologies.

Publications

Adaptive optics scanning laser ophthalmoscopy (AOSLO) measures in USH2A-related retinal degeneration

Jacque Duncan, Zendi Liang, Joseph Carroll, Jenna Cava, Jessica Wong, Michel Michaelides, Angelos Kalitzeos, Isabelle Audo, Kate Grieve, Nathaniel Norberg, Michel Paques, Allison Ayala, Travis Porco
Investigative Ophthalmology & Visual Science
21st June 2021

Multi-modal and multi-scale retinal imaging with angiography

Muhammend Faizan Shirazi, Jordi Andilla, Marina Cunquero, Nicolas Lefaudeux, Danilo Andrade De Jesus, Luisa Sanchéz Brea, Stefan Klein, Theo van Walsum, Kate Grieve, Michel Paques, Marie Elise Wistrup Torm, Michael Larsen, Pablo Loza-Alvarez, Xavier Levecq, Nicolas Chateau, Michael Pircher
Investigative Ophthalmology & Visual Science
21st June 2021

Adaptive-glasses Full-Field OCT for high-resolution retinal imaging over a large field-of-view

Investigative Ophthalmology & Visual Science
21st June 2021

Non invasive live imaging of a novel retinal pigment epithelium stress model with Dynamic Full-Field Optical Coherence Tomography

Kassandra Groux, Anna Verschueren, Céline Nanteau, Marilou Clémençon, Mathias Fink, José-Alain Sahel, Claude Boccara, Michel Paques, Sacha Reichman, Kate Grieve
19th June 2021

Assessing photoreceptor status in retinal dystrophies: from high resolution imaging to functional vision

José-Alain Sahel, Kate Grieve, Chloé Pagot, Colar Authié, Saddek Mohand Saïd, Michel Paques, Isabelle Audo, Karine Becker, Anne-Elisabeth Chaumet-Riffaud, Line Azoulay, Emmanuel Gutman, Thierry Léveillard, Christina Zeitz, Serge Picaud, Deniz Dalkara, Katia Marazova
American Journal of Ophthalmology
14th May 2021

Automatic diagnosis and biopsy classification with dynamic Full-Field OCT and machine learning

Thouvenin O, Jules Scholler, D Mandache, MC Mathieu, AB Lakhdar, Marie Darche, T Monfort, Claude Boccara, J Olivo-Marin, Kate Grieve, VM Yedid, Ebal Guillaume
3rd May 2021

High Resolution Multi-Modal and Multi-Scale Retinal Imaging for Clinical Settings

MF Shirazi, J Andilla, CP Valdes, N Lefaudeux, D andrade De Jesus, L Sanchez Brea, S Klein, T Van Walsum, Kate Grieve, Michel Paques, M Torm, M Larsen, P Loza-Alvarez, X Levecq, N Chateau, M Pircher
Bio-Optics: Design and Application
12th April 2021

Enhancing contrast of in-vivo human retinal ganglion cells with multi-offset adaptive optics scanning laser ophthalmoscope

Elena Gofas, Yuhua Rui, Pedro Mecê, Min Zhang, Valerie Snyder, Kari V Vienola, Daniel Lee, José-Alain Sahel, Kate Grieve, Ethan Rossi
OSA
12th April 2021

Adaptive glasses wavefront sensorless full-field OCT for high-resolution retinal imaging over a wide field-of-view

SPIE
5th March 2021

Retinal curvature correction with coherence gate shaping for full-field OCT high-resolution retinal imaging over a wide field-of-view

SPIE
5th March 2021

Dynamic full-field optical coherence tomography of retinal pigment epithelium cell cultures to model degenerative diseases

Kassandra Groux, Jules Scholler, Anna Verschueren, Marie Darche, Leyna Boucherit, Pedro Mecê, Valerie Fradot, Jean-Marie Chassot, Sacha Reichman, Michel Paques, Claude Boccara, Olivier Thouvenin, Kate Grieve
SPIE
5th March 2021

Optical Incoherence Tomography: a method to generate tomographic retinal cross-sections with non-interferometric adaptive optics ophthalmoscopes

SPIE
5th March 2021

Adaptive-glasses time-domain FFOCT for wide-field high-resolution retinal imaging with increased SNR

1st November 2020

Attenuation outer retinal bands on optical coherence tomography following macular edema: a possible manifestation of photoreceptor misalignment

Michel Paques, Florence Rossant, Lucia Finocchio, Kate Grieve, José-Alain Sahel, Alexandre Pedinielli, Sarah Mrejen
Retina
1st November 2020

Multimodal imaging of pre-Descemet corneal dystrophy

Munirah Alafaleq, Cristina Georgeon, Kate Grieve, Vincent M Borderie
Sage Journals
September 2020

Coherence gate shaping for wide field high-resolution in vivo retinal imaging with full-field OCT

Biomedical optics express
1st September 2020

Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids

Jules Scholler, Kassandra Groux, Olivier Goureau, José-Alain Sahel, Mathias Fink, Sacha Reichman, Claude Boccara, Kate Grieve
Light Sci Appl 9, 140 (2020)
17th August 2020

Optical Incoherence Tomography: a method to generate tomographic retinal cross-sections with non-interferometric imaging systems

August 2020

Super-resolution in-vivo retinal imaging using structured illumination ophthalmoscopy

Yann Lai-Tim, Laurent Mugnier, Lea Krafft, Antoine Chen, Cyril Petit, Pedro Mecê, Kate Grieve, Michel Paques, Serge Meimon
30th July 2020

Dynamic Full-Field OCT to image RPE cell cultures.

Kassandra Groux, Jules Scholler, Anna Verschueren, Marie Darche, Olivier Goureau , José-Alain Sahel, Mathias Fink , Michel Paques, Claude Boccara, Olivier Thouvenin , Sacha Reichman, Kate Grieve
Dynamic Full-Field OCT to image RPE cell cultures. Invest. Ophthalmol. Vis. Sci. 2020;61(7):1867.
June 2020

High resolution structural phenotyping of intermediate and advanced non-neovascular age-related macular degeneration.

Chiara Eandi, Valerie Snyder , Kate Grieve, Kunal Dansingani , Jay Chhablani, Grace Eddy, Andrew Eller, Joseph Martel , Thomas Friberg , Wei Chen, Yvette Perry Conley , José-Alain Sahel, Michel Paques, Ethan Rossi
Invest. Ophthalmol. Vis. Sci. 2020;61(7):210.
June 2020

A new method for visualizing drusen and their progression in adaptive optics ophthalmoscopy.

E Rossi, C Eandi, V Snyder, Kate Grieve, K Dansingani, J Chhablani, Sarah Mrejen, J Martel, José-Alain Sahel, Michel Paques
new method for visualizing drusen and their progression in adaptive optics ophthalmoscopy. Invest. Ophthalmol. Vis. Sci. 2020;61(7):203.
June 2020

Adaptive Optics SLO motion correction assisted by image similarity. Invest. Ophthalmol. Vis. Sci. 2020;61(7):227.

Danilo Andrade de Jesus , Luisa Sanchez Brea, Kate Grieve, Michel Paques, Nicolas Lefaudeux, Theo van Walsum, Stefan Klein
May 2020

Corneal stromal stem cells restore transparency after N 2 injury in mice. Stem Cells Translational Medicine 2020.

D Ghoubay , M Borderie, Kate Grieve, R Martos
7th May 2020

Real-time non-contact cellular imaging and angiography of human cornea and limbus with common-path full-field/SD-OCT.

Slava Mazlin, Xiao P , Jules Scholler, Irsch K, Kate Grieve, Fink M, Claude Boccara
Nature communications 11(1), 1-14
2020

Attenuation Outer Retinal Bands on Optical Coherence Tomography Following Macular EDEMA

Michel Paques, Florence Rossant, Lucia Finocchio , Kate Grieve, José-Alain Sahel, Alexandre Pedinielli, Sarah Mrejen
A Possible Manifestation of Photoreceptor Misalignment
7th January 2020

Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids. arXiv preprint.

arXiv:1912.04052, 2019 (in review Light: Science and Applications 2020).
2019

Multimodal Imaging Features of Schnyder Corneal Dystrophy.

Ghazal W, Georgeon C, Kate Grieve, Bouheraoua N, Borderie V
J Ophthalmol 2020.
31st December 2019

New article published in IEEE Transactions in Biomedical Engineering

"Highlighting directional reflectance properties of retinal substructures from D-OCT images" IEEE Transactions on Biomedical Engineering ( Early Access ) February 2019.
November 2019

Near infrared adaptive optics flood illumination retinal angiography

Elena Gofas, Pedro Mecê, Laurent Mugnier, Aurélie Montmerle Bonnefois, Cyril Petit, Kate Grieve, José-Alain Sahel, Michel Paques, Serge Meimon
"Near infrared adaptive optics flood illumination retinal angiography," Biomed. Opt. Express 10, 2730-2743 (2019)
1st June 2019

Higher adaptive optics loop rate enhances axial resolution in nonconfocal ophthalmoscopes

"Higher adaptive optics loop rate enhances axial resolution in nonconfocal ophthalmoscopes," Opt. Lett. 44, 2208-2211 (2019)
1st May 2019

Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT

Jules Scholler, Viacheslav Mazlin, Olivier Thouvenin, Kassandra Groux, Peng Xiao, José-Alain Sahel, Mathias Fink, Claude Boccara, Kate Grieve
"Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT," Biomed. Opt. Express 10, 731-746 (2019)
1st February 2019

Multimodal imaging of pre-Descemet corneal dystrophy. European J Opthalmol, 1120672119862505, 2019.

Alafaleq M, Georgeon C, Kate Grieve, Borderie V
2018

In vivo near-infrared autofluorescence imaging of retinal pigment epithelial cells with 757 nm excitation

"In vivo near-infrared autofluorescence imaging of retinal pigment epithelial cells with 757 nm excitation," Biomed. Opt. Express 9, 5946-5961 (2018)
1st December 2018

Directional variability of fundus lesions in acute macular neuroretinopathy

Retin Cases Brief Rep. 2018 Fall;12 Suppl 1:S19-S24. doi: 10.1097/ICB.0000000000000701.
2018

Adaptive optics ophthalmoscopy: Application to age-related macular degeneration and vascular diseases

Michel Paques, Serge Meimon, Florence Rossant, David Rosenbaum, Sarah Mrejen, Florian Sennlaub, Kate Grieve
Prog Retin Eye Res. 2018;66:1-16.
1st September 2018

Adaptive optics opthalmoscopy of dry age-related macular degeneration and vascular diseases

Prog Retin Eye Res. 2018 Sep;66:1-16. doi: 10.1016/j.preteyeres.2018.07.001. Epub 2018 Jul 17.
September 2018

New prospects in Adaptive-Optics Flood-Illumination retinal imaging

Adaptive Optics: Analysis, Methods & Systems, 2018 OTh4C. 4
2018

High loop rate adaptive optics flood illumination ophthalmoscope with structured illumination capability

Elena Gofas, Pedro Mecê, Cyril Petit, J. Jarosz, Laurent Mugnier, Aurélie Montmerle Bonnefois, Kate Grieve, José-Alain Sahel, Michel Paques, Serge Meimon
Appl. Opt. 57, 5635-5642 (2018)
10th July 2018

In vivo high-resolution human retinal imaging with wavefront-correctionless full-field OCT

Peng Xiao, Viacheslav Mazlin, Kate Grieve, José-Alain Sahel, Mathias Fink, Claude Boccara
Optica 5 (4), 409-412.
20th April 2018

Fixational eye movement: a negligible source of dynamic aberration

Biomedical Optics Express 9 (2), 717-727.
1st February 2018

In vivo high resolution human corneal imaging using full-field optical coherence tomography

Viacheslav Mazlin, Peng Xiao, E. Dalimier, Kate Grieve, K. Irsch, José-Alain Sahel, Mathias Fink, Claude Boccara
Biomedical Optics Express 9 (2), 557-568.
1st February 2018

Detection and Tracking of the Pores of the Lamina Cribrosa in Three Dimensional SD-OCT Data

ACIVS 2017, Antwerp, Belgium, September 2017
Antwerp, Belgium, 23rd November 2017

Stromal striae: a new insight into corneal physiology and mechanics

Kate Grieve, D. Ghoubay, C. Georgeon, R. Bocheux, G. Latour, M. Borderie, A. Nahas, TM. Nguyen, MC. Schanne-Klein, F. Andreiuolo, Vincent Borderie
Scientific Reports 7 (1), 13584 2017.
19th October 2017

Cell motility as contrast agent in retinal explant imaging with full-field optical coherence tomography

Olivier Thouvenin, Claude Boccara, Mathias Fink, José-Alain Sahel, Michel Paques, Kate Grieve
Invest Ophthalmol Vis Sci. 2017;58:4605???4615. DOI:10.1167/iovs.17-22375
September 2017

Automated Analysis of Directional Optical Coherence Tomography Images

ICIAR'17, Montreal, Canada, July 2017, vol. LNCS 10317, pp 524-532
Montreal, Canada, 2nd June 2017

Full-field OCT technique for high speed event-based optical flow and particle tracking.

X. Berthelon, G. Chenegros, N. Libert, José-Alain Sahel, Kate Grieve, R. Benosman
Opt Express. 2017. 29;25(11):12611-12621.
29th May 2017

Pupil motion analysis and tracking in ophthalmic systems equipped with wavefront sensing technology.

Serge Meimon, J. Jarosz, Cyril Petit, Elena Gofas, Kate Grieve, JM. Conan, B. Emica, Michel Paques, K. Irsch
Appl. Opt. 2017. 56, D66-D71.
20th March 2017

New Parameters in Assessment of Human Donor Corneal Stroma

M. Borderie, Kate Grieve, D. Ghoubay, C. Georgeon, C. De Sousa, L. Laroche, Vincent Borderie
Acta Ophthalmol. 2017. doi:10.1111/aos.13351
30th January 2017

En face coherence microscopy

Olivier Thouvenin, Kate Grieve, Peng Xiao, Claude Boccara
Biomed. Opt. Express 2017; 8, 622-639, special issue OCT. Invited paper.
10th January 2017

Imaging Microscopic Features of Keratoconic Corneal Morphology

Kate Grieve, C. Georgeon, F. Andreiuolo, AL.
Cornea. 2016;35(12):1621-1630. doi:10.1097/ICO.0000000000000979.
25th August 2016

Appearance of the retina with full-field optical coherence tomography

Kate Grieve, Olivier Thouvenin, A. Sengupta, Vincent Borderie, Michel Paques
Invest Ophthalmol Vis Sci. 2016;57:OCT96???OCT104. DOI:10.1167/iovs.15-18856
10th July 2016

Three-dimensional structure of the mammalian limbal stem cell niche.

Kate Grieve, D. Ghoubay, C. Georgeon, Olivier Thouvenin, N. Bouheraoua, Michel Paques, Vincent Borderie
Exp Eye Res. 2015 Nov;140:75-84. doi: 10.1016/j.exer.2015.08.003. Epub 2015 Aug 20
November 2015
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