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Pedro Mecê

 
Pedro Mecê

Tenured Researcher (CNRS)

Flood and Scanning Technology Full-Field OCT

 

My research work focuses on the development of optical methods for imaging, focusing and wavefront shaping in complex media such as biological tissues. I am particularly interested in the in-vivo human retina, as the eye is the only transparent optical window into our body, providing unique access to observe neural and vascular networks of retinal tissue at the cellular level. I am currently working on novel methods for Full-Field OCT and Adaptive Optics applied for in-vivo human retina imaging.

MSc, PhD.
PhD Topic: AO-corrected retinal laser surgery
Postdoc at Institut Langevin: in-vivo FF-OCT retinal imaging

Publications

Adaptive-glasses Full-Field OCT for high-resolution retinal imaging over a large field-of-view

Pedro Mecê, Jules Scholler, Kassandra Groux, Yao Cai, Michel Paques, Kate Grieve, Claude Boccara
Investigative Ophthalmology & Visual Science
21st June 2021
> https://iovs.arvojournals.org/article.aspx?articleid=2773292

Coherence gate shaping for wide field high-resolution in vivo retinal imaging with full-field OCT

Pedro Mecê, Kassandra Groux, Jules Scholler, Olivier Thouvenin, Mathias Fink, Kate Grieve, Claude Boccara
Biomedical optics express
1st September 2020
> https://www.osapublishing.org/DirectPDFAccess/6D4A1497-1549-4002

Optical Incoherence Tomography: a method to generate tomographic retinal cross-sections with non-interferometric imaging systems

Pedro Mecê, Elena Gofas, Michel Paques, Kate Grieve, Serge Meimon
August 2020
> https://doi.org/10.1364/BOE.396937
 
 

Characterization and Analysis of Retinal Axial Motion at High Spatiotemporal Resolution and Its Implication for Real-Time Correction in Human Retinal Imaging

Yao Cai, Kate Grieve, Pedro Mecê
12th July 2022
> https://www.ncbi.nlm.nih.gov/pubmed/35903318

Adaptive glasses wavefront sensorless Full-Field OCT for high-resolution in vivo retinal imaging over a wide FOV

Yao Cai, Jules Scholler, Kassandra Groux, Olivier Thouvenin, Claude Boccara, Pedro Mecê, Kate Grieve
Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC)
June 2022
> https://doi.org/10.1109/CLEO/Europe-EQEC52157.2021.9542127

Imaging the structure and dynamic activity of retinal microglia and macrophage-like cells in the living human eye

Yuhua Rui, Daniel MW Lee, Min Zhang, Valerie C Snyder, Rashmi Raghuraman, Elena Gofas, Pedro Mecê, Sanya Yadav, Pavan Tiruveedhula, Kate Grieve, José-Alain Sahel, Marie-Hélène Errera, Ethan A Rossi
bioRxiv
15th June 2022
> https://doi.org/10.1101/2022.04.30.490173

Design of a radial multi-offset detection pattern for in vivo phase contrast imaging of the inner retina in humans

Elena Gofas, Yuhua Rui, Pedro Mecê, Min Zhang, Valerie C. Snyder, Kari V. Vienola, Daniel M. W. Lee, José-Alain Sahel, Kate Grieve, Ethan A Rossi
Optica
Biomed. Opt. Express 13, 117-132 , 15th June 2022
> https://doi.org/10.1364/BOE.441808

Imaging retinal microglial cell dynamics in healthy and diseased eyes in vivo with adaptive optics

Ethan Rossi*, Yuhua Rui, Daniel MW Lee, Min Zhang, Valerie Snyder*, Elena Gofas, Pedro Mecê, Rashmi Raghuraman, Sanya Yadav, Pavan Tiruveedhula, Kate Grieve, Marie-Hélène Errera
1st June 2022
> https://iovs.arvojournals.org/article.aspx?articleid=2779029

Retinal axial motion analysis and implications for real-time correction in human retinal imaging

Yao Cai, Kate Grieve, Pedro Mecê
Biorxiv
1st January 2022
> https://doi.org/10.1101/2022.01.07.475424

Partial-Field Illumination Ophthalmoscope: improving the contrast of a camera-based retinal imager

Lea Krafft, Elena Gofas, Yann Lai-Tim, Michel Paques, Laurent Mugnier, Olivier Thouvenin, Pedro Mecê, Serge Meimon
2nd September 2021
> https://arxiv.org/abs/2109.08571

High-resolution retinal imaging over a large field-of-view with adaptive-glasses Full-Field OCT

Kate Grieve, Jules Scholler, Kassandra Groux, Yao Cai, Michel Paques, Claude Boccara, Pedro Mecê
Investigative Ophthalmology & Visual Science
23rd August 2021
> https://iovs.arvojournals.org/article.aspx?articleid=2776687

Enhancing contrast of in-vivo human retinal ganglion cells with multi-offset adaptive optics scanning laser ophthalmoscope

Elena Gofas, Yuhua Rui, Pedro Mecê, Min Zhang, Valerie Snyder, Kari V Vienola, Daniel Lee, José-Alain Sahel, Kate Grieve, Ethan Rossi
OSA
12th April 2021
> https://www.osapublishing.org/abstract.cfm?uri=NTM-2021-NTu1C.6

Adaptive glasses wavefront sensorless full-field OCT for high-resolution retinal imaging over a wide field-of-view

Pedro Mecê, Jules Scholler, Kassandra Groux, Kate Grieve, Claude Boccara
SPIE
5th March 2021
> https://doi.org/10.1117/12.2576689

Retinal curvature correction with coherence gate shaping for full-field OCT high-resolution retinal imaging over a wide field-of-view

Pedro Mecê, Kassandra Groux, Jules Scholler, Kate Grieve, Claude Boccara
SPIE
5th March 2021
> https://doi.org/10.1117/12.2576687

Dynamic full-field optical coherence tomography of retinal pigment epithelium cell cultures to model degenerative diseases

Kassandra Groux, Jules Scholler, Anna Verschueren, Marie Darche, Leyna Boucherit, Pedro Mecê, Valerie Fradot, Jean-Marie Chassot, Sacha Reichman, Michel Paques, Claude Boccara, Olivier Thouvenin, Kate Grieve
SPIE
5th March 2021
> https://doi.org/10.1117/12.2581048

Adaptive-glasses time-domain FFOCT for wide-field high-resolution retinal imaging with increased SNR

Jules Scholler, Kassandra Groux, Kate Grieve, Claude Boccara, Pedro Mecê
1st November 2020

Super-resolution in-vivo retinal imaging using structured illumination ophthalmoscopy

Yann Lai-Tim, Laurent Mugnier, Lea Krafft, Antoine Chen, Cyril Petit, Pedro Mecê, Kate Grieve, Michel Paques, Serge Meimon
30th July 2020
> arXiv:2007.16028

Retinal Capillary Plexus Pattern and Density from Fovea to Periphery Measured in Healthy Eyes with Swept-Source Optical Coherenc

Carlo Lavia , Pedro Mecê, Marco Nassisi, Sophie Bonnin, Jennifer Marie-Louise, Aude Couturier , Ali Erginay, Ramin Tadayoni, Alain Gaudric
"Retinal Capillary Plexus Pattern and Density from Fovea to Periphery Measured in Healthy Eyes with Swept-Source Optical Coherence Tomography Angiography." Sci Rep 10, 1474 (2020).
30th January 2020
> https://www.nature.com/articles/s41598-020-58359-y
> https://doi.org/https://doi.org/10.1038/s41598-0

High-resolution in-vivo human retinal imaging using full-field OCT with optical stabilization of axial motion

Pedro Mecê, Jules Scholler, Kassandra Groux, Claude Boccara
"High-resolution in-vivo human retinal imaging using full-field OCT with optical stabilization of axial motion," Biomed. Opt. Express 11, 492-504 (2020)
2019
> https://doi.org/https://doi.org/10.1364/BOE.3813

Near infrared adaptive optics flood illumination retinal angiography

Elena Gofas, Pedro Mecê, Laurent Mugnier, Aurélie Montmerle Bonnefois, Cyril Petit, Kate Grieve, José-Alain Sahel, Michel Paques, Serge Meimon
"Near infrared adaptive optics flood illumination retinal angiography," Biomed. Opt. Express 10, 2730-2743 (2019)
1st June 2019
> https://www.osapublishing.org/boe/abstract.cfm?uri=boe-10-6-2730

Higher adaptive optics loop rate enhances axial resolution in nonconfocal ophthalmoscopes

Pedro Mecê, Elena Gofas, Cyril Petit, Frédéric Cassaing, José-Alain Sahel, Michel Paques, Kate Grieve, Serge Meimon
"Higher adaptive optics loop rate enhances axial resolution in nonconfocal ophthalmoscopes," Opt. Lett. 44, 2208-2211 (2019)
1st May 2019
> https://www.osapublishing.org/ol/abstract.cfm?uri=ol-44-9-2208

New prospects in Adaptive-Optics Flood-Illumination retinal imaging

Serge Meimon, Elena Gofas, Pedro Mecê, Cyril Petit, Kate Grieve, L. Mugnier, José-Alain Sahel, Michel Paques
Adaptive Optics: Analysis, Methods & Systems, 2018 OTh4C. 4
2018
> https://www.osapublishing.org/abstract.cfm?uri=AOMS-2018-OTh4C.4
> https://doi.org/10.1364/AOMS.2018.OTh4C.4

High loop rate adaptive optics flood illumination ophthalmoscope with structured illumination capability

Elena Gofas, Pedro Mecê, Cyril Petit, J. Jarosz, Laurent Mugnier, Aurélie Montmerle Bonnefois, Kate Grieve, José-Alain Sahel, Michel Paques, Serge Meimon
Appl. Opt. 57, 5635-5642 (2018)
10th July 2018
> https://www.osapublishing.org/ao/abstract.cfm?uri=ao-57-20-5635

Fixational eye movement: a negligible source of dynamic aberration

Pedro Mecê, J. Jarosz, JM. Conan, Cyril Petit, Kate Grieve, Michel Paques, Serge Meimon
Biomedical Optics Express 9 (2), 717-727.
1st February 2018
> https://www.osapublishing.org/boe/abstract.cfm?uri=boe-9-2-717&origin=search
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